What causes heart disease?
The heart is a muscle that requires a steady supply of oxygen in order to pump blood effectively through the body. Oxygen is supplied to the heart by blood that flows through the coronary arteries. Some types of heart disease damage or block the coronary arteries and the flow of oxygen to the heart. Other forms of heart disease damage or impair the functioning of the heart and blood vessels. These disorders include:
Abnormal electrical conduction in the heart causing cardiac arrhythmias or abnormal heart rhythms. These include ventricular tachycardia, heart blocks, ventricular fibrillation, asystole, supraventricular tachycardia, and bradycardia.
Atherosclerosis, a buildup of plaque on the walls of the coronary arteries. Atherosclerosis narrows the coronary arteries and results in angina. It can also lead to the formation of a blood clot that blocks blood flow to the heart (heart attack).
Birth defects, also called congenital heart or blood vessel defects. These include atrial septal defect, coarctation of the aorta, and atrioventricular septal defect.
Heart damage, such as heart failure or cardiomyopathy, that weakens the pumping action of the heart
Heart valve abnormalities, which are also called heart valve disorders. Heart valve disorders include mitral valve insufficiency, mitral valve prolapse, mitral valve stenosis, tricuspid valve insufficiency, and tricuspid valve stenosis.
Infection and inflammation caused by myocarditis or pericarditis
What are the risk factors for heart disease?
A number of factors are thought to increase your chances of having heart disease. These risk factors include:
African American, Hispanic American, or Native American ancestry
Excessive alcohol consumption
Exposure of a baby to certain maternal diseases during pregnancy
Exposure of a baby to certain toxins during pregnancy
Family history of heart disease
High blood pressure (hypertension)
History of atherosclerosis
History of diabetes
Long-term stress
Male gender and postmenopausal females aged 45 years and older
Obesity and sedentary lifestyle
Smoking
Having high levels of certain substances in the body, which can be seen on blood tests, can also increase the risk for heart disease. These include:
High cholesterol, which can lead to atherosclerosis
High C-reactive protein (CRP) level, which increases atherosclerosis
High homocysteine level, which is associated with heart disease; however, no causal link has been established
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